Abstract: The experiment was conducted for the evaluation of the performance of seed potato to organic fertilizers. Two potato varieties viz. Asterix (V1) and Diamant (V2) were subjected to different inorganic fertilizers viz. Control (T1), Cowdung (T2), Annapurna organic fertilizer (T3), 75% Annapurna organic fertilizer + 25 % Vermicompost (T4) and Vermicompost (T5). Early 80% emergence was found from T1 (V1: 26.3 days; V2: 23.3 days) while early tuberization from T2 for V1 (36.0 days) and T1 for V2 (29.0 days). Both varieties performed differently to the organic fertilizers used in the experiment. T4 was the best for V1 (14.3 kg per plot and 28.8 t.ha-1) while T3 was best for V2 (14.1 kg per plot and 28.3 t.ha-1). Asterix yielded more tuber than diamant variety. The performances of both varieties were not varied significantly among the treatments for different graded tuber except for 28–55 mm graded tuber in asterix. From the study it is suggested to use of 75% Annapurna organic fertilizer + 25% Vermicompost for asterix variety with BARI recommended inorganic fertilizers in order to get more yielding seed potato.